Press
01/31/2024 | Adipo Therapeutics completes $1.9M seed funding bridge to advance obesity treatment
We are excited about the potential of Adipo to advance the treatment of obesity care by increasing energy expenditure through brown fat. Our hope for the 100 million people in the U.S. living with obesity is to advance the management of their disease by increasing the calories their body burns.
Adipo Scientific Publications
07/20/14 | Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity
Pengpeng Bi | Nature Medicine
08/06/14 | Notch signaling as a novel regulator of metabolism.
Bi P, Kuang S | Trends Endocrinol Metab
11/09/15 | Biodegradable Polymeric Microsphere-Based Drug Delivery for Inductive Browning of Fat
Chunhui Jiang | Frontiers in Endocrinology
07/05/17 | Dibenzazepine-Loaded Nanoparticles Induce Local Browning of White Adipose Tissue to Counteract Obesity
Chunhui Jiang | ScienceDirect
12/01/19 | Polymeric Carriers for Controlled Drug Delivery in Obesity Treatment
Di Huang | ScienceDirect
09/04/20 | In vitro evaluation of clinical candidates of γ-secretase inhibitors: effects on Notch inhibition and promoting beige adipogenesis and mitochondrial biogenesis.
Huang, D., Qiu, J., Kuang, S., Deng, M. | Pharm Res
11/04/21 | Nanoparticle-Mediated Inhibition of Notch Signaling Promotes Mitochondrial Biogenesis and Reduces Subcutaneous Adipose Tissue Expansion in Pigs
Huang D, Narayanan N, Cano-Vega M, Jia Z, Ajuwon K, Kuang S, Deng M | iScience
Brown Adipose Tissue Publications
04/09/09 | Functional Brown Adipose Tissue in Healthy Adults
Kirsi A. Virtanen, M.D., Ph.D., Martin E. Lidell, Ph.D., Janne Orava, B.S., Mikael Heglind, M.S., Rickard Westergren, M.S., Tarja Niemi, M.D., Markku Taittonen, M.D., Ph.D., Jukka Laine, M.D., Ph.D., Nina-Johanna Savisto, M.S., Sven Enerbäck, M.D., Ph.D., and Pirjo Nuutila, M.D., Ph.D. | The New England Journal of Medicine
05/24/21 | The Role of Brown Adipose Tissue Dysfunction in the Development of Cardiovascular Disease
Hong-Jin Chen, Ting Meng, Ping-Jin Gao, Cheng-Chao Ruan | https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2021.652246/full
07/01/22 | The Heartwarming Effect of Brown Adipose Tissue
Kelsey M. Pinckard, Kristin I. Stanford | Molecular Pharmacology
03/29/24 | Experts Aim to Use Brown Fat to Burn Fat More Effectively
Ute Eppinger | Medscape